Description

5-Bromopyrimidine-2-Carboxylic Acid is a high-purity, versatile brominated heterocyclic building block essential for modern synthetic chemistry. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. Pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers need it for its reactive carboxylic acid and halogen functionalities, which enable precise coupling and derivatization reactions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, antiviral agents, and other small molecule therapeutics.
• Agrochemical Research: Used in creating novel fungicides, herbicides, and plant growth regulators.
• Ligand & Catalyst Development: Serves as a precursor for chelating ligands and organometallic catalysts in asymmetric synthesis.
• Material Science: Incorporated into organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology: Utilized in the synthesis of probes, tags, and molecular tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and reference standards.

Basic Information

Product Name	5-Bromopyrimidine-2-Carboxylic Acid
CAS No.	37131-87-6
Molecular Formula	C5H3BrN2O2
Molecular Weight	202.99 g/mol
Synonyms	2-Pyrimidinecarboxylic acid, 5-bromo-; 5-Bromo-2-pyrimidinecarboxylic acid; 5-Bromopyrimidine-2-carboxylate; 2-Carboxy-5-bromopyrimidine; 5-Bromopyrimidine-2-carboxylic acid; 37131-87-6; 5-Br-Pym-2-COOH
EINECS	Contact for details

Quality Control

Our 5-Bromopyrimidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.