Description

(E)-4,6-Dichloro-2-Styrylquinazoline CAS NO 36950-52-4 is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile quinazoline scaffold.
• Agrochemical Development: Serves as a building block for creating new herbicides, fungicides, or plant growth regulators.
• Organic Synthesis: Employed in academic and industrial laboratories for constructing complex heterocyclic systems and exploring novel chemical reactions.
• Material Science Research: Investigated as a potential component for organic electronic materials due to its conjugated styryl-quinazoline structure.

Basic Information

Product Name	(E)-4,6-Dichloro-2-Styrylquinazoline
CAS No.	36950-52-4
Molecular Formula	C₁₆H₁₀Cl₂N₂
Molecular Weight	301.17 g/mol
Synonyms	4,6-Dichloro-2-[(E)-2-phenylethenyl]quinazoline; 2-[(E)-Styryl]-4,6-dichloroquinazoline; (E)-2-(4,6-Dichloroquinazolin-2-yl)-1-phenylethene; 4,6-Dichloro-2-styrylquinazoline; 2-Styryl-4,6-dichloroquinazoline; 36950-52-4; 4,6-Dichloro-2-styryl-quinazoline
EINECS	Contact for details

Quality Control

Our (E)-4,6-Dichloro-2-Styrylquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive and should be stored away from light to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.