Description

Gentamicin B CAS NO 36889-15-3 is a key aminoglycoside antibiotic component, valued for its potent bactericidal activity against a broad spectrum of Gram-negative and some Gram-positive bacteria. Its primary commercial importance lies in its role as a critical intermediate and reference standard in the pharmaceutical industry for the research, development, and quality control of antibiotic formulations. This high-purity compound is essential for manufacturers and research institutions focused on anti-infective therapeutics, microbiology, and analytical chemistry.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of complex antibiotic formulations.
• Reference Standard: Used in analytical laboratories for the identification, assay, and impurity profiling of gentamicin mixtures via HPLC, LC-MS, and other chromatographic methods.
• Microbiological Research: Employed in studies investigating bacterial resistance mechanisms, antibiotic efficacy, and structure-activity relationships (SAR) of aminoglycosides.
• Quality Control & Assurance: Essential for pharmaceutical QC departments to ensure the potency, purity, and consistency of gentamicin-based drug products against pharmacopeial standards (USP, EP).
• Veterinary Medicine: Used in the development and testing of antibacterial treatments for animals.

Basic Information

Product Name	Gentamicin B
CAS No.	36889-15-3
Molecular Formula	C20H41N5O7
Molecular Weight	463.57 g/mol
Synonyms	Gentamicin B1; Gentamicin B Sulfate; Antibiotic G 418; Geneticin; 2-Deoxystreptamine derivative; O-3-Deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl-(1→4)]-; Garamycin component B; Sch 9724
EINECS	253-265-6

Quality Control

Our Gentamicin B is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets high-grade specifications suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing results against relevant pharmacopeial references (USP, EP) are provided to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.