Description

D-Tryptophan Monohydrochloride is the hydrochloride salt of the D-isomer of the essential amino acid tryptophan. This specific enantiomer is a critical chiral building block and intermediate in pharmaceutical synthesis and biochemical research. It is primarily utilized by manufacturers in the life sciences sector for the development of active pharmaceutical ingredients (APIs), peptide synthesis, and as a component in specialized microbiological media. The compound's high purity and defined stereochemistry are essential for ensuring the efficacy and safety of final products.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of specific peptides, peptidomimetics, and other bioactive molecules.
• Biochemical Research: Used in enzymatic studies, metabolic pathway analysis, and as a standard for analytical methods like HPLC and mass spectrometry.
• Microbiology & Cell Culture: A component of defined culture media for selective growth of microorganisms or specialized cell lines requiring the D-isomer.
• Asymmetric Synthesis: Serves as a starting material or catalyst ligand in stereoselective chemical reactions.
• Reference Standard: Employed as a high-purity standard in quality control laboratories for pharmaceutical and nutritional analysis.

Basic Information

Product Name	D-Tryptophan Monohydrochloride
CAS No.	36760-44-8
Molecular Formula	C11H13ClN2O2
Molecular Weight	240.69 g/mol
Synonyms	(R)-2-Amino-3-(1H-indol-3-yl)propanoic acid hydrochloride; D-(-)-Tryptophan hydrochloride; (R)-Tryptophan hydrochloride; D-Tryptophan HCl; D-TRP-HCl; (2R)-2-Azaniumyl-3-(1H-indol-3-yl)propanoate chloride
EINECS	Contact for details

Quality Control

Our D-Tryptophan Monohydrochloride is manufactured under a strict quality management system. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical and research applications. Certificates of Analysis (COA) documenting identity, purity (by HPLC), enantiomeric excess, and other critical parameters are available upon request. We can supply material compliant with in-house specifications or tailor quality parameters to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Enantiomeric Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.