Description

5-Bromopyrimidine N-Oxide is a versatile brominated heterocyclic building block, specifically a pyrimidine derivative. This compound is of significant value in advanced organic synthesis due to its reactive bromine atom and the electron-withdrawing N-oxide moiety, which facilitates selective cross-coupling and functionalization reactions. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules. The compound is supplied with a high level of purity to ensure consistent performance in sensitive applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for creating functionalized polymers, ligands for catalysis, and organic electronic materials.
• Cross-Coupling Reactions: Employed in Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce the pyrimidine N-oxide scaffold into more complex structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme functions.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	5-Bromopyrimidine N-Oxide
CAS No.	36529-69-8
Molecular Formula	C4H3BrN2O
Molecular Weight	174.98 g/mol
Synonyms	5-Bromopyrimidine 1-Oxide; 5-Bromopyrimidine N-Oxide; Pyrimidine, 5-bromo-, 1-oxide; 5-Bromo-1-oxidopyrimidin-1-ium; 5-Bromopyrimidine-1-oxide
EINECS	Contact for details

Quality Control

Our 5-Bromopyrimidine N-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We are committed to meeting the stringent requirements of research and development as well as cGMP standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.