Description

Cyclo[L-Ala-n-Methyl-L-Leu-L-Leu-3-[(E)-1-Propenyl]-L-Ala-1-(1,1-Dimethyl-2-Propenyl)-L-Trp-n-Methyl-L-Leu-3-Nitro-L-Tyr-] is a complex, synthetic cyclic peptide derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a sophisticated molecular scaffold for investigating peptide-protein interactions, enzyme inhibition, and novel therapeutic pathways. It is primarily needed by research institutions, biotechnology firms, and pharmaceutical companies engaged in drug discovery, particularly for developing targeted therapies and studying bioactive peptide conformations.

Application

• Pharmaceutical Research & Drug Discovery: Serves as a key intermediate or lead compound in the development of novel peptide-based therapeutics.
• Biochemical Tool Compound: Used in enzymatic studies, receptor binding assays, and as a probe to investigate specific biological pathways.
• Structural Biology Studies: Employed in research focused on peptide conformation, stability, and structure-activity relationships (SAR).
• Academic & Institutional Research: Utilized in university and government labs for fundamental studies in organic chemistry, medicinal chemistry, and peptide science.
• Preclinical Development: Acts as a candidate molecule for in vitro and in vivo efficacy and toxicity testing.

Basic Information

Product Name	Cyclo[L-Ala-n-Methyl-L-Leu-L-Leu-3-[(E)-1-Propenyl]-L-Ala-1-(1,1-Dimethyl-2-Propenyl)-L-Trp-n-Methyl-L-Leu-3-Nitro-L-Tyr-]
CAS No.	36528-64-0
Molecular Formula	C58H81N9O10
Molecular Weight	1064.3 g/mol
Synonyms	Cyclo(Ala-N-Me-Leu-Leu-3-[(E)-1-Propenyl]-Ala-1-(1,1-Dimethyl-2-propenyl)-Trp-N-Me-Leu-3-Nitro-Tyr); Cyclic Peptide 36528-64-0; CAS 36528-64-0; Cyclo[L-Ala-N-methyl-L-Leu-L-Leu-3-[(E)-1-propenyl]-L-Ala-1-(1,1-dimethyl-2-propenyl)-L-Trp-N-methyl-L-Leu-3-nitro-L-Tyr]; 3-Nitro-L-tyrosine-containing cyclic peptide; N-Methylleucine cyclic peptide derivative; Cyclo(Ala-MeLeu-Leu-CinnamylAla-PrenylTrp-MeLeu-NitroTyr)
EINECS	Contact for details

Quality Control

Our Cyclo[L-Ala-n-Methyl-L-Leu-L-Leu-3-[(E)-1-Propenyl]-L-Ala-1-(1,1-Dimethyl-2-Propenyl)-L-Trp-n-Methyl-L-Leu-3-Nitro-L-Tyr-] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.