Description

Buspirone is a high-purity, synthetic organic compound belonging to the azapirone chemical class, widely recognized for its specific pharmacological activity. This active pharmaceutical ingredient (API) is critical for the development and manufacturing of modern anxiolytic medications, offering a distinct therapeutic profile. It is essential for pharmaceutical manufacturers, research institutions, and fine chemical suppliers serving the global healthcare sector. Our supply of Buspirone CAS NO 36505-84-7 is characterized by stringent quality control and reliable scalability to meet industrial demands.

Application

Buspirone is primarily utilized in the pharmaceutical industry, with its applications extending into advanced research and development.

• Active Pharmaceutical Ingredient (API): Core component in the formulation of anxiolytic tablets for the treatment of generalized anxiety disorder (GAD).
• Pharmaceutical Intermediates: Serves as a key synthetic intermediate in the production of related psychotherapeutic agents.
• Reference Standard: Used in analytical laboratories for quality control, method development, and calibration in HPLC and GC assays.
• Clinical Research: Employed in preclinical and clinical studies investigating new therapeutic applications or novel drug delivery systems.
• Generic Drug Manufacturing: Sourced by manufacturers producing bioequivalent generic versions of branded anxiolytic medications.

Basic Information

Product Name	Buspirone
CAS No.	36505-84-7
Molecular Formula	C21H31N5O2
Molecular Weight	385.50 g/mol
Synonyms	8-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione; MJ 9022-1; Bespar; Buspar; Buspimen; Narol; Ansial; Ansiced; Anxiron; Sporilin; 8-[4-(4-Pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione
EINECS	253-101-1

Quality Control

Our Buspirone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide full traceability and support regulatory submissions with comprehensive documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.