Description

3-Methylhistamine Dihydrochloride is a high-purity, pharmaceutically relevant derivative of histamine, widely utilized as a critical biochemical tool and reference standard. This compound is essential for researchers and manufacturers requiring a stable, water-soluble form of 3-methylhistamine for precise analytical and synthetic applications. It is primarily used in neuroscience, pharmacology, and diagnostic development for studying histamine receptors, metabolic pathways, and developing related assays.

Application

• Pharmacological Research: Acts as a key reference standard and biochemical tool in the study of histamine H3 receptor activity and function.
• Diagnostic Development: Used in the research and production of immunoassays and diagnostic kits for measuring histamine and its metabolites.
• Neuroscience Studies: Employed in experimental models to investigate the role of histaminergic systems in the central nervous system.
• Metabolic Pathway Analysis: Serves as a standard in chromatography (HPLC, LC-MS) for the quantification of histamine metabolites in biological samples.
• Chemical Synthesis: An important intermediate or starting material for the synthesis of more complex histamine-related compounds and potential drug candidates.
• Quality Control: Used as an analytical reference standard in pharmaceutical QC laboratories to ensure the purity and identity of related products.

Basic Information

Product Name	3-Methylhistamine Dihydrochloride
CAS No.	36475-47-5
Molecular Formula	C6H13N3·2HCl
Molecular Weight	216.11 g/mol
Synonyms	1-Methyl-4-(2-aminoethyl)imidazole dihydrochloride; 3-Methylhistamine 2HCl; 3-MH dihydrochloride; 1-Methyl-4-(β-aminoethyl)imidazole dihydrochloride; 3-Methylhistamine hydrochloride; 3-Methylhistamine HCl; 1-Methyl-4-(2-aminoethyl)-1H-imidazole dihydrochloride; (1-Methyl-1H-imidazol-4-yl)ethanamine dihydrochloride
EINECS	Contact for details

Quality Control

Our 3-Methylhistamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other validated methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every lot to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.