Description

5-Bromo-2,4-Dichloropyrimidine is a versatile halogenated pyrimidine building block of significant importance in advanced organic synthesis. Its core value lies in its ability to undergo selective substitution reactions, making it a critical intermediate for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and kinase inhibitor drug discovery programs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its reactive halogen sites for further functionalization.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Ligand and Catalyst Development: Employed in the creation of novel pyrimidine-based ligands for metal-organic frameworks (MOFs) and catalytic systems.
• Chemical Biology Probe Synthesis: Utilized to create tagged or modified nucleobase analogs for studying biological processes and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Bromo-2,4-Dichloropyrimidine
CAS No.	36082-50-5
Molecular Formula	C4HBrCl2N2
Molecular Weight	242.87 g/mol
Synonyms	2,4-Dichloro-5-bromopyrimidine; 5-Bromo-2,4-dichloropyrimidine; Pyrimidine, 5-bromo-2,4-dichloro-; 5-Brom-2,4-dichlorpyrimidin; 5-Bromo-2,4-dichloro-pyrimidine; 2,4-Dichloro-5-bromo-pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,4-Dichloropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.