Description

H-Leu-Ile-Oh is a high-purity dipeptide derivative composed of L-Leucine and L-Isoleucine residues. This compound serves as a critical building block and intermediate in advanced organic synthesis, particularly for the development of complex peptides and peptidomimetics. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, high-quality raw materials for drug discovery and development processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel therapeutic peptides and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or reagent in proteomics, enzymology, and metabolic pathway studies.
• Peptide Synthesis: Serves as a protected dipeptide unit in solid-phase and solution-phase peptide synthesis (SPPS).
• Drug Discovery: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and library construction.
• Cosmetic Peptides: A potential ingredient in the formulation of advanced skincare and anti-aging products.
• Academic & Industrial R&D: Fundamental material for chemical biology research and process development.

Basic Information

Product Name	H-Leu-Ile-Oh
CAS No.	36077-41-5
Molecular Formula	C12H24N2O3
Molecular Weight	244.33 g/mol
Synonyms	H-Leu-Ile-OH; L-Leucyl-L-isoleucine; Leu-Ile; N-(3-Methylbutanoyl)-L-isoleucine; (2S)-2-[[(2S)-2-Amino-4-methylpentanoyl]amino]-3-methylpentanoic acid; H-L-Leu-L-Ile-OH; L-Leu-L-Ile; N-L-Leucyl-L-isoleucine
EINECS	Contact for details

Quality Control

Our H-Leu-Ile-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Chiral Purity (HPLC)	≥99.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.