Description

Di-Dnpyr-L-Lysine is a chemically modified derivative of the essential amino acid L-lysine, featuring two dinitrophenyl (Dnp) protecting groups. This compound is a critical intermediate and research chemical, valued for its role in peptide synthesis and biochemical studies where selective protection and deprotection of amino acid side chains are required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing novel peptide-based therapeutics and conducting advanced proteomic analysis.

Application

• Peptide Synthesis Intermediate: Serves as a key building block in solid-phase and solution-phase peptide synthesis, where the Dnp groups protect the lysine side chain amines.
• Biochemical Research: Used in studies of enzyme kinetics, protein-protein interactions, and the development of affinity labels or inhibitors targeting lysine residues.
• Proteomics & Labeling Reagents: Can be employed in the design of chemical probes for mass spectrometry-based proteomic analysis to identify and quantify proteins.
• Pharmaceutical Development: Acts as a precursor in the research and development of peptide drugs, vaccines, and diagnostic agents.
• Cross-linking Studies: Useful in investigating molecular cross-linking mechanisms due to the reactive nature of the protected functional groups.

Basic Information

Product Name	Di-Dnpyr-L-Lysine
CAS No.	35899-65-1
Molecular Formula	C18H18N6O8
Molecular Weight	446.37 g/mol
Synonyms	N6,N6-Bis(2,4-dinitrophenyl)-L-lysine; Di-DNP-L-lysine; L-Lysine, N6,N6-bis(2,4-dinitrophenyl)-; N6,N6-Di-Dnp-L-lysine; Bis(2,4-dinitrophenyl)-L-lysine; DNP-Lys(DNP); Lys(Dnp)2; (2S)-2-Amino-6-[[(2,4-dinitrophenyl)amino](2,4-dinitrophenyl)amino]hexanoic acid
EINECS	Contact for details

Quality Control

Our Di-Dnpyr-L-Lysine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity research standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on dried basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.