Description

Benzenamine, 3-Bromo-4-Chloro-5-Fluoro- is a high-purity, multi-halogenated aniline derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the halogen atoms contribute to bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate for producing high-performance, light-fast azo dyes and complex organic pigments.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for creating complex biaryl structures.
• Chemical Research & Development: Essential tool compound in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.

Basic Information

Product Name	Benzenamine, 3-Bromo-4-Chloro-5-Fluoro-
CAS No.	35754-27-9
Molecular Formula	C6H4BrClFN
Molecular Weight	224.46 g/mol
Synonyms	3-Bromo-4-chloro-5-fluoroaniline; 5-Fluoro-3-bromo-4-chloroaniline; 3-Bromo-4-chloro-5-fluorobenzenamine; Aniline, 3-bromo-4-chloro-5-fluoro-; 1-Amino-3-bromo-4-chloro-5-fluorobenzene; 2-Bromo-1-chloro-6-fluoro-4-aminobenzene; 3-Br-4-Cl-5-F-C6H2NH2
EINECS	Contact for details

Quality Control

Our Benzenamine, 3-Bromo-4-Chloro-5-Fluoro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.