Description

Cyclo(L-Phe-L-Val) CAS NO 35590-86-4 is a synthetic cyclic dipeptide, also known as a diketopiperazine (DKP), composed of phenylalanine and valine residues. This compound serves as a crucial pharmacophore and building block in medicinal chemistry and drug discovery. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors for developing novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: Key scaffold for the synthesis of protease inhibitors, receptor antagonists, and other bioactive molecules.
• Medicinal Chemistry Research: Used as a constrained peptide mimic to study structure-activity relationships (SAR) and improve metabolic stability.
• Bioconjugation & Peptide Engineering: Serves as a linker or structural element in the design of peptide-drug conjugates and engineered biomolecules.
• Cosmetic & Personal Care Actives: Investigated for potential use in anti-aging and skin-conditioning formulations due to its peptide nature.
• Biochemical Tool Compound: Employed in enzymatic assays and as a reference standard in analytical laboratories.
• Material Science: Explored as a component in the development of supramolecular structures and functional organic materials.

Basic Information

Product Name	Cyclo(L-Phe-L-Val)
CAS No.	35590-86-4
Molecular Formula	C14H18N2O2
Molecular Weight	246.31 g/mol
Synonyms	Cyclo(Phe-Val); Cyclo(L-phenylalanyl-L-valyl); 3-Benzyl-6-isopropyl-2,5-piperazinedione; (3S,6S)-3-Benzyl-6-(isopropyl)-2,5-diketopiperazine; Phe-Val Diketopiperazine; L-Phenylalanyl-L-valine anhydride; DKPs; Cyclic dipeptide; 2,5-Diketopiperazine derivative
EINECS	Contact for details

Quality Control

Our Cyclo(L-Phe-L-Val) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity verification, and identity confirmation to ensure it meets stringent specifications. Certificates of Analysis (COA) detailing all test results are available upon request. We support development and cGMP-grade requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (by chiral HPLC)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.