Description

L-Proline, 1-(Aminoiminomethyl)- (9Ci) is a specialized proline derivative, a non-proteinogenic amino acid analog of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a versatile chiral building block and intermediate for the development of novel bioactive molecules, including enzyme inhibitors and peptide mimetics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating innovative therapeutic agents and complex chemical libraries.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly enzyme inhibitors and receptor modulators.
• Peptidomimetic Research: Used to design and synthesize modified peptides with enhanced stability, bioavailability, or specific biological activity.
• Bioconjugation Chemistry: Acts as a functionalized linker or spacer molecule in the development of antibody-drug conjugates (ADCs) or other bioconjugates.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective organic reactions to construct complex molecular architectures.
• Chemical Biology Probes: Useful in the creation of molecular probes for studying biological pathways and protein functions.
• Academic & Industrial R&D: Serves as a valuable reagent for exploratory research in medicinal chemistry and organic synthesis.

Basic Information

Product Name	L-Proline, 1-(Aminoiminomethyl)- (9Ci)
CAS No.	35404-57-0
Molecular Formula	C7H13N3O2
Molecular Weight	171.20 g/mol
Synonyms	1-Amidinoproline; (S)-1-Amidinoproline; L-1-Amidinoproline; 1-Carbamimidoyl-L-proline; 1-Guanidinoproline; (S)-1-Carbamimidoylpyrrolidine-2-carboxylic acid; 35404-57-0; L-Proline, 1-(aminoiminomethyl)-
EINECS	Contact for details

Quality Control

Our L-Proline, 1-(Aminoiminomethyl)- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.