Description

4-(1,1,2,2-Tetrafluoroethoxy)Benzaldehyde is a high-purity fluorinated aromatic aldehyde, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique tetrafluoroethoxy substituent imparts enhanced lipophilicity and metabolic stability, making it a valuable building block for the development of novel active compounds. This specialty chemical is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides, where the fluorine moiety enhances biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays (LCDs) and optical devices.
• Polymer & Material Science: Building block for synthesizing specialty polymers, coatings, and advanced materials with specific surface properties and chemical resistance.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions, such as Suzuki-Miyaura couplings, and as a substrate for exploring new fluorination methodologies.

Basic Information

Product Name	4-(1,1,2,2-Tetrafluoroethoxy)Benzaldehyde
CAS No.	35295-36-4
Molecular Formula	C9H6F4O2
Molecular Weight	222.14 g/mol
Synonyms	p-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde; 4-(Perfluoroethoxy)benzaldehyde; Benzaldehyde, 4-(1,1,2,2-tetrafluoroethoxy)-; 1,1,2,2-Tetrafluoroethyl 4-formylphenyl ether; 4-Formylphenyl 1,1,2,2-tetrafluoroethyl ether
EINECS	Contact for details

Quality Control

Our 4-(1,1,2,2-Tetrafluoroethoxy)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.