Description

1-(5-Fluoro-2-Methoxy-Phenyl)-Ethylamine is a versatile chiral amine building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both fluorine and methoxy substituents on the aromatic ring, makes it a critical intermediate for constructing complex, biologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and specialty performance chemicals.
• Academic and R&D: Utilized in university and corporate research laboratories for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	1-(5-Fluoro-2-Methoxy-Phenyl)-Ethylamine
CAS No.	35253-23-7
Molecular Formula	C9H12FNO
Molecular Weight	169.20 g/mol
Synonyms	α-Methyl-5-fluoro-2-methoxybenzylamine; (1-(5-Fluoro-2-methoxyphenyl)ethyl)amine; 5-Fluoro-2-methoxy-α-methylbenzylamine; 1-(5-Fluoro-2-methoxyphenyl)ethan-1-amine; Benzenemethanamine, 5-fluoro-α-methyl-2-methoxy-; (R/S)-1-(5-Fluoro-2-methoxyphenyl)ethylamine; 5-Fluoro-2-methoxyamphetamine precursor
EINECS	Contact for details

Quality Control

Every batch of 1-(5-Fluoro-2-Methoxy-Phenyl)-Ethylamine is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiopure grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.