Description

2(1H)-Pyrimidinethione, 5-Fluoro- (9Ci) is a fluorinated pyrimidine derivative, a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which combines a thione group with a fluorine substituent, enabling precise modifications in drug discovery and materials science. This high-purity intermediate is primarily needed by research institutions and pharmaceutical companies engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel fluorinated drug candidates, particularly in oncology and antiviral therapies.
• Agrochemical Research: Used in the synthesis of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Chemical Biology Probe: Serves as a building block for creating molecular probes to study enzyme mechanisms and biological pathways.
• Material Science Precursor: Employed in the development of specialty polymers and organic electronic materials requiring specific heterocyclic architectures.
• Academic & Industrial R&D: Essential for methodological studies in organic chemistry, including novel coupling reactions and heterocycle functionalization.

Basic Information

Product Name	2(1H)-Pyrimidinethione, 5-Fluoro- (9Ci)
CAS No.	35250-11-4
Molecular Formula	C4H3FN2S
Molecular Weight	130.15 g/mol
Synonyms	5-Fluoro-2(1H)-pyrimidinethione; 5-Fluoropyrimidine-2-thiol; 5-Fluoro-2-mercaptopyrimidine; 5-Fluoro-2-pyrimidinethiol; 2-Mercapto-5-fluoropyrimidine; 35250-11-4; 5-Fluoro-1H-pyrimidine-2-thione
EINECS	Contact for details

Quality Control

Every batch of 2(1H)-Pyrimidinethione, 5-Fluoro- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.