Description

3-Ethylhistidine is a non-proteinogenic amino acid derivative, a modified form of the essential amino acid histidine. This compound is valued for its role as a biochemical precursor and research tool in the study of enzyme mechanisms and metabolic pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications ranging from peptide synthesis to advanced biochemical research.

Application

• Pharmaceutical Research & Development: As a key intermediate or building block in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Studies: Used as a substrate or inhibitor in enzymatic studies to investigate histidine-related metabolic pathways and enzyme kinetics.
• Peptide Synthesis: Serves as a specialized amino acid derivative in solid-phase and solution-phase peptide synthesis for creating custom peptides with specific properties.
• Metabolomics & Biomarker Research: Employed as a reference standard in analytical methods (HPLC, LC-MS) for the identification and quantification of metabolites in biological samples.
• Nutritional Science Research: Investigated for its potential effects and roles in specialized nutritional formulations and metabolic studies.
• Diagnostic Reagent Development: A potential component in the formulation of reagents and assays for clinical diagnostics and research kits.

Basic Information

Product Name	3-Ethylhistidine
CAS No.	35166-49-5
Molecular Formula	C8H13N3O2
Molecular Weight	183.21 g/mol
Synonyms	3-Ethyl-L-histidine; L-Histidine, 3-ethyl-; (2S)-2-Amino-3-(1-ethyl-1H-imidazol-4-yl)propanoic acid; 1-Ethyl-4-imidazolepropanoic acid, α-amino-; 3-Ethylhistidine dihydrochloride (salt form); 3-Ethyl-His; 3-N-Ethylhistidine
EINECS	Contact for details

Quality Control

Our 3-Ethylhistidine is manufactured under a quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profiles. Our quality commitment supports applications requiring high-purity biochemicals for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.