Description

2-Nitro-4,5-Bis(trifluoromethyl)benzenamine is a specialized aromatic amine derivative featuring nitro and trifluoromethyl substituents, which confer unique electronic and steric properties. This compound is valued for its role as a critical synthetic intermediate in the development of advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl groups improve lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for functional dyes, liquid crystals, and organic electronic materials due to its electron-withdrawing character.
• Cross-Coupling Reactions: An important substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex amine derivatives.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new synthetic methodologies and fluorination chemistry.

Basic Information

Product Name	2-Nitro-4,5-Bis(trifluoromethyl)Benzenamine
CAS No.	35010-32-3
Molecular Formula	C9H4F6N2O2
Molecular Weight	286.14 g/mol
Synonyms	2-Nitro-4,5-bis(trifluoromethyl)aniline; 4,5-Bis(trifluoromethyl)-2-nitroaniline; 2-Nitro-α,α,α,α',α',α'-hexafluoro-p-xylidine; Benzenamine, 2-nitro-4,5-bis(trifluoromethyl)-; 2-Nitro-4,5-di(trifluoromethyl)aniline
EINECS	Contact for details

Quality Control

Every batch of 2-Nitro-4,5-Bis(trifluoromethyl)Benzenamine is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with exacting customer and research standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store this material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC Area %)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.