Description

Pyroglutamyl-Phenylalanyl-Prolinamide is a synthetic tripeptide derivative with the CAS number 34783-35-2. This compound is of significant interest in advanced pharmaceutical research and development, particularly in the field of neuropeptide and hormone analog studies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in peptide synthesis and therapeutic agent discovery.

Application

• Pharmaceutical Research: Serves as a key intermediate or reference standard in the development of novel neuropeptide and hormone-based therapeutics.
• Biochemical Studies: Used as a tool compound to investigate peptide-receptor interactions, signal transduction pathways, and enzyme inhibition mechanisms.
• Peptide Synthesis: Acts as a building block for the solid-phase or solution-phase synthesis of more complex peptide chains and analogs.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control of peptide-based products using techniques like HPLC and MS.
• Neuroscience Research: Investigated for potential effects on neurological functions and as a model for studying peptide stability and blood-brain barrier penetration.

Basic Information

Product Name	Pyroglutamyl-Phenylalanyl-Prolinamide
CAS No.	34783-35-2
Molecular Formula	C19H24N4O4
Molecular Weight	372.42 g/mol
Synonyms	pGlu-Phe-Pro-NH2; Pyroglutamylphenylalanylprolinamide; 5-Oxo-L-prolyl-L-phenylalanyl-L-prolinamide; L-Pyroglutamyl-L-phenylalanyl-L-prolinamide; TRH Fragment (1-3); Thyrotropin-Releasing Hormone (1-3); (S)-1-((S)-2-((S)-5-Oxopyrrolidine-2-carboxamido)-3-phenylpropanamido)pyrrolidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our Pyroglutamyl-Phenylalanyl-Prolinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods, purity assessment by HPLC, and determination of residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.