Description

4-[10,11-Dihydro-8-(Methylthio)Dibenzo[B,F]Thiepin-10-Yl]Piperazinium Methanesulphonate is a high-purity, non-proprietary pharmaceutical intermediate and research chemical of significant interest in medicinal chemistry. This compound matters for its role as a key synthetic precursor in the development of novel therapeutic agents, particularly within the central nervous system (CNS) and psychopharmacological research domains. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in advanced organic synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel tricyclic and heterocyclic compounds with potential therapeutic activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new candidates targeting neurological and psychiatric disorders.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.
• Biochemical Research: Employed in pharmacological studies to investigate receptor binding affinity and mechanism of action of related drug molecules.
• Fine Chemical Synthesis: A versatile synthon for constructing complex molecular architectures in custom synthesis and contract manufacturing.

Basic Information

Product Name	4-[10,11-Dihydro-8-(Methylthio)Dibenzo[B,F]Thiepin-10-Yl]Piperazinium Methanesulphonate
CAS No.	34775-83-2
Molecular Formula	C21H26N2O3S3
Molecular Weight	450.63 g/mol
Synonyms	8-(Methylthio)-10-[4-(piperazin-1-yl)]-10,11-dihydrodibenzo[b,f]thiepin Methanesulfonate; Perathiepin Methanesulfonate; Metitepine Methanesulfonate; 10-[4-(Piperazin-1-yl)]-8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin Methanesulfonate; 34775-83-2; UNII-6J6E5K6V8U; Methanesulfonic acid compound with 8-(methylthio)-10-(4-piperazinyl)-10,11-dihydrodibenzo[b,f]thiepin (1:1)
EINECS	Contact for details

Quality Control

Our production of 4-[10,11-Dihydro-8-(Methylthio)Dibenzo[B,F]Thiepin-10-Yl]Piperazinium Methanesulphonate adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure compliance with research and pharmaceutical intermediate standards. Certificates of Analysis (COA) with complete chromatographic data are available upon request, providing full traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.