Description

Ethyl 4-Chloro-2-(Pyrrolidin-1-Yl)Pyrimidine-5-Carboxylate is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a chloro and a pyrrolidinyl substituent, makes it an invaluable intermediate for constructing complex nitrogen-containing heterocycles. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides that require specific pyrimidine scaffolds.
• Material Science: Building block for creating specialized polymers, ligands, or organic electronic materials with tailored properties.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Chemical Library Synthesis: Employed in combinatorial chemistry and high-throughput screening to generate diverse compound libraries for biological testing.

Basic Information

Product Name	Ethyl 4-Chloro-2-(Pyrrolidin-1-Yl)Pyrimidine-5-Carboxylate
CAS No.	34750-25-9
Molecular Formula	C11H14ClN3O2
Molecular Weight	255.70 g/mol
Synonyms	Ethyl 4-chloro-2-(1-pyrrolidinyl)-5-pyrimidinecarboxylate; 4-Chloro-2-(pyrrolidin-1-yl)pyrimidine-5-carboxylic acid ethyl ester; 5-Pyrimidinecarboxylic acid, 4-chloro-2-(1-pyrrolidinyl)-, ethyl ester; Ethyl 4-chloro-2-pyrrolidin-1-ylpyrimidine-5-carboxylate; 2-(1-Pyrrolidinyl)-4-chloro-5-pyrimidinecarboxylic acid ethyl ester; CAS 34750-25-9
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-2-(Pyrrolidin-1-Yl)Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.