Description

Ethyl 4-Chloro-2-Morpholinopyrimidine-5-Carboxylate is a high-purity pyrimidine derivative, a crucial advanced pharmaceutical intermediate. Its value lies in its role as a key building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in kinase inhibitor development. This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and fine chemical sectors seeking reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its heterocyclic core structure.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and new compound library generation.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Ethyl 4-Chloro-2-Morpholinopyrimidine-5-Carboxylate
CAS No.	34750-23-7
Molecular Formula	C11H14ClN3O3
Molecular Weight	271.70 g/mol
Synonyms	4-Chloro-2-morpholin-4-ylpyrimidine-5-carboxylic acid ethyl ester; Ethyl 4-chloro-2-(morpholin-4-yl)pyrimidine-5-carboxylate; 2-Morpholino-4-chloropyrimidine-5-carboxylic acid ethyl ester; 4-Chloro-2-morpholinopyrimidine-5-carboxylic acid ethyl ester; 34750-23-7; UNII-7J7K2D8Q0K; 7J7K2D8Q0K; SCHEMBL218021; CTK8C0898
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-2-Morpholinopyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.