Description

Boc-Lys(Tfa)-Osu is a protected amino acid derivative widely used as a key building block in peptide synthesis. This compound matters for its role in introducing the lysine residue with orthogonal protecting groups, enabling complex, multi-step solid-phase and solution-phase peptide assembly. Pharmaceutical researchers and fine chemical manufacturers need it for the development of therapeutic peptides, diagnostic agents, and biochemical probes.

Application

• Pharmaceutical Intermediates: Critical building block for the synthesis of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Used to modify proteins, antibodies, or other biomolecules by introducing functional handles via the lysine side chain.
• Research & Development: Essential reagent in academic and industrial labs for exploring novel peptide structures and their biological activities.
• Combinatorial Chemistry: A valuable component in libraries for high-throughput screening to discover new drug candidates.
• Proteomics & Diagnostics: Employed in the preparation of labeled peptides for mass spectrometry standards or diagnostic assays.
• Material Science: Used to create peptide-functionalized surfaces or polymers for biomedical applications.

Basic Information

Product Name	Boc-Lys(Tfa)-Osu
CAS No.	34695-46-0
Molecular Formula	C₁₉H₂₈F₃N₃O₈
Molecular Weight	483.44 g/mol
Synonyms	Nα-Boc-Nε-trifluoroacetyl-L-lysine N-hydroxysuccinimide ester; Boc-Lys(Tfa)-OSu; (2,5-Dioxopyrrolidin-1-yl) (2S)-6-{[(trifluoroacetyl)amino]-2-{[(2-methylpropan-2-yl)oxy]carbonyl}amino}hexanoate; N-tert-Butoxycarbonyl-Nε-trifluoroacetyl-L-lysine N-succinimidyl ester; Boc-Lys(TFA)-OSu; Boc-L-Lys(Tfa)-Osu; N-Boc-N'-TFA-L-lysine N-hydroxysuccinimide ester
EINECS	Contact for details

Quality Control

Our Boc-Lys(Tfa)-Osu is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	-15.0° to -18.0° (c=1 in DMF)
Water Content (KF)	≤ 0.5%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.