Description

Poly-L-Isoleucine is a synthetic homopolymer of the essential amino acid L-Isoleucine, forming a polypeptide chain with a defined molecular weight range. This engineered biopolymer is valued for its role in advanced research and development, particularly in creating biomimetic materials and studying protein folding and peptide interactions. It serves as a critical building block for scientists and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors who require high-purity, well-characterized amino acid polymers.

Application

• Biomedical Research: Used as a model compound for studying protein aggregation, peptide self-assembly, and the biophysical properties of hydrophobic amino acid sequences.
• Drug Delivery Systems: Investigated as a component in the design of novel polymeric carriers for controlled drug release due to its biocompatibility and degradability.
• Biomaterial Development: Serves as a raw material for creating synthetic peptides, hydrogels, and scaffolds for tissue engineering applications.
• Enzyme & Protein Studies: Acts as a substrate or inhibitor analog in enzymatic assays and protein interaction studies.
• Cosmeceutical Formulations: Incorporated into high-end skincare products for its potential film-forming and moisturizing properties.
• Nutritional Science Research: Utilized in metabolic studies and as a standard in analytical method development for amino acid analysis.

Basic Information

Product Name	Poly-L-Isoleucine
CAS No.	34464-35-2
Molecular Formula	(C6H13NO2)n
Molecular Weight	Variable (based on polymerization degree 'n')
Synonyms	Poly(Isoleucine); L-Isoleucine Homopolymer; Poly(isoleucine) hydrochloride (salt form); P(Ile); PI; Poly-L-Ile; Isoleucine Polymer; Poly(isoleucine) (L-form)
EINECS	Contact for details

Quality Control

Our Poly-L-Isoleucine is produced under controlled conditions to ensure batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques, including HPLC for assay and impurity profiling, NMR for structural confirmation, and amino acid analysis. A Certificate of Analysis (COA) detailing specific results for purity, molecular weight distribution, and residual solvents is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation. For long-term storage, consider desiccant use and inert atmosphere sealing.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Molecular Weight (Avg.)	As per customer grade (e.g., 1kDa - 10kDa)
Loss on Drying	≤ 5.0 %
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.