Description

Boc-D-Ala-Osu CAS NO 34404-33-6 is a high-purity, protected amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring precise stereochemical control and efficient coupling reactions. It is primarily utilized in the pharmaceutical, biotechnology, and research sectors for the development of novel therapeutic peptides, APIs, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key reagent for the controlled incorporation of D-alanine residues into peptide chains, enabling the creation of peptides with enhanced metabolic stability.
• Solution-Phase Peptide Synthesis: Used in the synthesis of complex peptides and small proteins where solution-phase methodologies are preferred.
• Pharmaceutical Intermediate: Serves as a vital intermediate in the research and production of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Bioconjugation and Labeling: Facilitates the site-specific modification of peptides and proteins for diagnostic, imaging, or drug delivery applications.
• Biochemical Research: Employed in academic and industrial R&D for studying peptide structure-activity relationships (SAR) and enzyme-substrate interactions.
• Production of Peptide Mimetics: Used to synthesize peptidomimetics, which are designed to mimic natural peptides but with improved pharmacological properties.

Basic Information

Product Name	Boc-D-Ala-Osu
CAS No.	34404-33-6
Molecular Formula	C12H18N2O6
Molecular Weight	286.28 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-alanine N-hydroxysuccinimide ester; Boc-D-alanine N-succinimidyl ester; Boc-D-Ala-OSu; N-Boc-D-alanine succinimidyl ester; tert-Butyloxycarbonyl-D-alanine N-hydroxysuccinimide ester; D-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester; Boc-D-Ala-ONSu
EINECS	Contact for details

Quality Control

Our Boc-D-Ala-Osu is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, NMR for structural confirmation, and loss on drying. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.