Description

1-(2-Amino-Ethyl)-1H-Pyrimidine-2,4-Dione Hydrochloride is a high-purity organic salt derivative of a pyrimidine nucleobase, serving as a critical building block in advanced chemical synthesis. Its primary value lies in its functionalized structure, which provides a reactive amine group and a protected heterocyclic core, enabling its use in the development of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of nucleoside analogs, active pharmaceutical ingredients (APIs), and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used as a building block in the multi-step synthesis of complex target molecules for clinical development.
• Biochemical Research: Employed in life science research for studying enzyme mechanisms, nucleic acid chemistry, and as a substrate analog.
• Agrochemical Development: Serves as an intermediate in the creation of new herbicides, fungicides, or plant growth regulators that utilize modified pyrimidine structures.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing high-value, specialty chemicals with specific chiral or functional properties.

Basic Information

Item	Details
Product Name	1-(2-Amino-Ethyl)-1H-Pyrimidine-2,4-Dione Hydrochloride
CAS No.	34386-73-7
Molecular Formula	C6H10N3O2·HCl
Molecular Weight	193.62 g/mol (Free base: 157.16 g/mol)
Synonyms	N-(2-Aminoethyl)uracil hydrochloride; 2,4-Dioxo-1-(2-aminoethyl)-1,2,3,4-tetrahydropyrimidine hydrochloride; 1-(2-Aminoethyl)uracil hydrochloride; Uracil-1-ethylamine hydrochloride; N1-(2-Aminoethyl)uracil HCl; 1-(β-Aminoethyl)uracil hydrochloride; N1-(2-Aminoethyl)-2,4(1H,3H)-pyrimidinedione hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Amino-Ethyl)-1H-Pyrimidine-2,4-Dione Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for our customers' global supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.