Description

Dobutamine CAS NO 34368-04-2 is a synthetic catecholamine and a direct-acting inotropic agent used primarily as a pharmaceutical active ingredient. It is a critical compound for the treatment of acute heart failure and cardiogenic shock, where it increases cardiac output by stimulating β-1 adrenergic receptors. This product is essential for pharmaceutical manufacturers and research institutions developing cardiovascular therapies and conducting pharmacological studies.

Application

• Pharmaceutical API: Primary use as the active pharmaceutical ingredient in injectable formulations for the treatment of cardiac decompensation.
• Hospital Emergency Medicine: A key component in critical care for managing low cardiac output in settings like intensive care units (ICUs) and emergency rooms.
• Cardiovascular Research: Used in preclinical and clinical research to study cardiac function, adrenergic receptor activity, and hemodynamic responses.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical laboratories.
• Veterinary Medicine: Applied in veterinary cardiology for similar inotropic support in animals.
• Drug Formulation Development: Utilized in R&D for developing new delivery systems, such as stable infusion solutions.

Basic Information

Product Name	Dobutamine
CAS No.	34368-04-2
Molecular Formula	C18H23NO3
Molecular Weight	301.38 g/mol
Synonyms	Dobutamine Hydrochloride (common salt form); (±)-4-[2-[[1-Methyl-3-(4-hydroxyphenyl)propyl]amino]ethyl]pyrocatechol; Dobutrex (trade name); Inotrex; (RS)-Dobutamine; DL-Dobutamine; 1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-
EINECS	251-975-5

Quality Control

Our Dobutamine is manufactured under strict quality management systems, targeting compliance with pharmacopeial standards such as USP and EP. Each batch undergoes comprehensive analytical testing including identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) documenting purity, related substances, and other critical parameters is provided with every shipment to ensure traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.