Description

Pglu-L-Tyr-Nh2 CAS NO 34368-03-1 is a specialized dipeptide derivative, specifically pyroglutamyl-L-tyrosine amide, used as a key intermediate in advanced pharmaceutical and biochemical research. This compound is valued for its role in the synthesis of complex peptides and as a building block for developing novel therapeutic agents and diagnostic tools. It is primarily required by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on peptide-based drug discovery and development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or reference standard in enzymatic studies and metabolic pathway investigations.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Neuroscience Research: Investigated for its potential role in neuropeptide analogs and central nervous system (CNS) targeted compounds.
• Cosmetic Peptide Development: Explored as a precursor for bioactive peptides in advanced skincare and cosmeceutical formulations.
• Diagnostic Reagent Manufacturing: Utilized in the production of specialized reagents for clinical diagnostics and assay kits.

Basic Information

Item	Detail
Product Name	Pglu-L-Tyr-Nh2
CAS No.	34368-03-1
Molecular Formula	C₁₄H₁₇N₃O₄
Molecular Weight	291.30 g/mol
Synonyms	Pyroglutamyl-L-tyrosine amide; 5-Oxo-L-prolyl-L-tyrosinamide; L-Pyroglutamyl-L-tyrosine amide; Pglu-Tyr-NH₂; pGlu-Tyr-NH2; NSC 334855; Pyr-L-Tyr-NH2; 5-Oxo-Pro-Tyr-NH2
EINECS	Contact for details

Quality Control

Our Pglu-L-Tyr-Nh2 is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a low-humidity environment. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.