Description

H-Ala-Phe-Pro-Oh is a high-purity tripeptide derivative, specifically the C-terminal carboxylic acid form of the sequence Alanine-Phenylalanine-Proline. This compound serves as a critical building block and intermediate in advanced pharmaceutical research and peptide synthesis. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of more complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or substrate in enzymatic studies, proteomics research, and metabolic pathway analysis.
• Peptide Library Construction: A fundamental component in solid-phase and solution-phase peptide synthesis for creating diverse compound libraries for screening.
• Cosmetic Peptide Synthesis: Potential intermediate in the production of bioactive peptides for advanced skincare and cosmetic formulations.
• Academic & Industrial R&D: Serves as a model compound for studying peptide structure-activity relationships (SAR) and stability.

Basic Information

Product Name	H-Ala-Phe-Pro-Oh
CAS No.	34327-70-3
Molecular Formula	C₁₇H₂₃N₃O₄
Molecular Weight	333.38 g/mol
Synonyms	Ala-Phe-Pro-OH; L-Alanyl-L-phenylalanyl-L-proline; AFG-OH; H-Ala-Phe-Pro-OH tripeptide; Alanine-Phenylalanine-Proline; 2-[(2S)-2-[[(2S)-2-Aminopropanoyl]amino]-3-phenylpropanoyl]-1-pyrrolidinecarboxylic acid; L-Ala-L-Phe-L-Pro-OH; Acyl Carrier Protein (65-74) fragment
EINECS	Contact for details

Quality Control

Our H-Ala-Phe-Pro-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.