Description

(17α)-3β-[(4-Amino-3-o-Methyl-2,4,6-Trideoxy-α-L-Arabino-Hexopyranosyl)Oxy]-14-Hydroxy-5α-Card-20(22)-Enolide is a high-purity, structurally complex cardenolide glycoside derivative. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, especially within the cardiovascular and oncology domains.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel cardiac glycosides and other steroidal drugs.
• Biochemical Research: Used as a reference standard or active agent in studies investigating sodium-potassium ATPase (Na+/K+-ATPase) inhibition and related cellular pathways.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new compounds with optimized efficacy and reduced toxicity profiles.
• API Development: Acts as a key starting material or advanced intermediate in the development of new Active Pharmaceutical Ingredients (APIs) for heart failure and arrhythmia treatments.
• Academic Research: Utilized in university and institutional labs for pharmacological and toxicological investigations of cardenolide derivatives.

Basic Information

Product Name	(17α)-3β-[(4-Amino-3-o-Methyl-2,4,6-Trideoxy-α-L-Arabino-Hexopyranosyl)Oxy]-14-Hydroxy-5α-Card-20(22)-Enolide
CAS No.	34303-94-1
Molecular Formula	C₃₀H₄₇NO₈
Molecular Weight	549.70 g/mol
Synonyms	3β-[(4-Amino-3-O-methyl-2,4,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-14-hydroxy-5α-card-20(22)-enolide; 3β-[(4-Amino-3-O-methyl-2,4,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-14-hydroxy-5α-card-20(22)-enolide (17α); 17α-3β-[(4-Amino-3-O-methyl-2,4,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-14-hydroxy-5α-card-20(22)-enolide; Digitoxigenin 3-O-4-amino-3-O-methyl-2,4,6-trideoxy-α-L-arabino-hexopyranoside derivative; Cardenolide amino sugar conjugate; 34303-94-1
EINECS	Contact for details

Quality Control

Our (17α)-3β-[(4-Amino-3-o-Methyl-2,4,6-Trideoxy-α-L-Arabino-Hexopyranosyl)Oxy]-14-Hydroxy-5α-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide Certificates of Analysis (COA) with detailed results for all critical parameters, ensuring traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.