Description

Boc-Pro-Gly-Ome CAS NO 34290-72-7 is a protected dipeptide building block, specifically the methyl ester of Boc-Pro-Gly-OH. This compound is a critical intermediate in solid-phase and solution-phase peptide synthesis, enabling the controlled elongation of peptide chains. It is primarily utilized by research institutions and pharmaceutical companies for the development of novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Peptide Synthesis Intermediate: A key building block for the automated and manual synthesis of custom peptides containing proline-glycine sequences.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs targeting various diseases.
• Bioconjugation: Serves as a spacer or linker molecule in the creation of peptide-protein or peptide-small molecule conjugates.
• Biochemical Tool Development: Employed to create substrates for enzyme studies (e.g., protease assays) or labeled peptides for imaging.
• Academic Research: Fundamental tool in university and institutional labs for studying peptide structure, function, and folding.
• Combinatorial Chemistry: Used in libraries for high-throughput screening to identify bioactive peptide leads.

Basic Information

Product Name	Boc-Pro-Gly-Ome
CAS No.	34290-72-7
Molecular Formula	C₁₃H₂₂N₂O₅
Molecular Weight	286.33 g/mol
Synonyms	Boc-L-Prolyl-glycine methyl ester; (2S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid-(2-aminoacetyl) methyl ester; N-(tert-Butoxycarbonyl)-L-prolylglycine methyl ester; Boc-L-Pro-Gly-OMe; Boc-Pro-Gly-OMe; tert-Butoxycarbonyl-L-prolylglycine methyl ester; N-Boc-L-prolylglycine methyl ester; Methyl N-[(tert-butoxy)carbonyl]-L-prolylglycinate
EINECS	Contact for details

Quality Control

Our Boc-Pro-Gly-Ome is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via spectroscopic methods. We provide Certificates of Analysis (COA) with detailed specifications for trace solvents, moisture content, and assay value, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	-60° to -66° (c=1 in methanol)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.