Description

N(Alpha)-Acetylarginine Methylamide is a chemically modified derivative of the amino acid arginine, featuring acetylation at the α-amino group and amidation of the carboxyl group. This specific modification makes it a valuable building block and intermediate in advanced biochemical research and pharmaceutical development. It is particularly essential for researchers and manufacturers in the fields of peptide synthesis, enzyme substrate studies, and metabolic pathway investigation.

Application

• Peptide Synthesis Intermediate: Serves as a key protected arginine derivative for the solid-phase and solution-phase synthesis of complex peptides and proteins.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving arginine-metabolizing enzymes like nitric oxide synthase (NOS) and arginase.
• Pharmaceutical Development: Acts as a precursor or model compound in the research and development of novel therapeutic agents targeting cardiovascular, immune, and neurological systems.
• Metabolite Standard: Employed as a reference standard in analytical chemistry (HPLC, LC-MS) for the quantification of arginine derivatives in biological samples.
• Cell Culture & Nutrition: Investigated for its potential role as a specialized nutrient or signaling molecule in cell culture media formulations.

Basic Information

Product Name	N(Alpha)-Acetylarginine Methylamide
CAS No.	34276-26-1
Molecular Formula	C9H19N5O3
Molecular Weight	245.28 g/mol
Synonyms	N-α-Acetylarginine Methylamide; N-Acetyl-L-arginine Methylamide; Ac-Arg-NHMe; L-Nα-Acetylargininamide, Methyl-; N-Acetyl-L-arginine methylamide; N(Alpha)-Acetyl-L-arginine methylamide; N-Acetyl-L-arginine-N'-methylamide; Nα-Acetyl-L-arginine methylamide
EINECS	Contact for details

Quality Control

Our N(Alpha)-Acetylarginine Methylamide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.