Description

H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Oh is a high-purity nonapeptide sequence, also known as Angiotensin I (1-9), with the CAS registry number 34273-12-6. This compound serves as a critical biochemical tool and a key intermediate in renin-angiotensin system (RAS) research and pharmaceutical development. It is essential for researchers and manufacturers in the fields of cardiovascular pharmacology, peptide synthesis, and diagnostic assay development who require a reliable and well-characterized reference standard.

Application

• Biochemical Research: A fundamental reference standard for studying the renin-angiotensin aldosterone system (RAAS), enzyme kinetics, and peptide hormone metabolism.
• Pharmaceutical R&D: Used as a key intermediate and analytical standard in the development of antihypertensive drugs, ACE inhibitors, and angiotensin receptor blockers (ARBs).
• Diagnostic Manufacturing: Serves as a critical antigen and calibrator in the production of immunoassay kits for measuring angiotensin peptides and related enzymes.
• Academic Studies: Employed in university and institutional laboratories for cardiovascular research, signal transduction studies, and physiological pathway analysis.
• Peptide Synthesis: Acts as a building block or a comparative standard for the custom synthesis of longer peptide chains and analogs within the angiotensin family.
• Quality Control: Utilized as a system suitability standard in HPLC and LC-MS methods to ensure the accuracy and precision of analytical procedures for peptide analysis.

Basic Information

Product Name	H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Oh
CAS No.	34273-12-6
Molecular Formula	C53H78N18O14
Molecular Weight	1151.3 g/mol
Synonyms	Angiotensin I (1-9); Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His; DRVYIHPFH; H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-OH; Angiotensin I Fragment 1-9; Nonapeptide Angiotensin (1-9); Angiotensin I (human) (1-9); [Asp1, Arg2, Val3, Tyr4, Ile5, His6, Pro7, Phe8, His9]-Angiotensin I
EINECS	Contact for details

Quality Control

Our H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.