Description

H-Gly-D-Phe-Oh CAS NO 34258-14-5 is a high-purity dipeptide derivative, specifically the D-enantiomer of phenylalanine coupled to glycine. This compound is a critical chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is essential for pharmaceutical R&D, particularly in developing therapeutic peptides, enzyme inhibitors, and advanced drug delivery systems.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of active pharmaceutical ingredients (APIs), especially peptide-based drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce a D-phenylalanine residue, influencing peptide stability and bioactivity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and for probing structure-activity relationships (SAR) in medicinal chemistry.
• Proteomics & Diagnostics: Can be utilized in the development of specialized reagents, affinity tags, or standards for mass spectrometry and diagnostic assays.
• Cosmeceutical Applications: Potential use in the design of bioactive peptides for advanced skincare and anti-aging formulations.

Basic Information

Product Name	H-Gly-D-Phe-Oh
CAS No.	34258-14-5
Molecular Formula	C11H14N2O3
Molecular Weight	222.24 g/mol
Synonyms	Glycyl-D-phenylalanine; D-Phenylalanylglycine; H-Gly-D-Phe-OH; Gly-D-Phe; (R)-2-((2-Aminoacetamido)-3-phenylpropanoic acid; N-Glycyl-D-phenylalanine; D-Phe-Gly; Glycine-D-phenylalanine dipeptide
EINECS	Contact for details

Quality Control

Our H-Gly-D-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets exacting standards for research and cGMP-grade applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% D-isomer
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.