Description

2,5-Di(1,1,2,2,2-Pentafluoroethoxy)Aniline is a specialized fluorinated aniline derivative, a key building block in advanced organic synthesis. Its unique structure, featuring two pentafluoroethoxy substituents, imparts exceptional electronic properties and chemical stability, making it invaluable for creating high-performance materials. This compound is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and pesticides where the fluorine atoms enhance bioavailability and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a core component for creating fluorinated liquid crystals and electron-transport/hole-blocking layers in organic light-emitting diodes (OLEDs) due to its electron-withdrawing character.
• Specialty Polymer Monomer: Incorporated into high-performance polymers, such as polyimides and polyarylates, to improve thermal stability, chemical resistance, and dielectric properties.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized fluorinated dyes and pigments with enhanced lightfastness and unique chromatic properties.
• Cross-coupling Reactions: The aniline moiety makes it a suitable substrate for Buchwald-Hartwig amination and other palladium-catalyzed cross-coupling reactions to construct complex molecules.

Basic Information

Product Name	2,5-Di(1,1,2,2,2-Pentafluoroethoxy)Aniline
CAS No.	34065-82-2
Molecular Formula	C10H5F10NO2
Molecular Weight	361.14 g/mol
Synonyms	2,5-Bis(pentafluoroethoxy)aniline; 2,5-Bis(1,1,2,2,2-pentafluoroethoxy)benzenamine; 1-Amino-2,5-bis(pentafluoroethoxy)benzene; Aniline, 2,5-bis(pentafluoroethoxy)-; 2,5-Di(pentafluoroethoxy)aniline; 2,5-Di(PFE)Aniline; 34065-82-2 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 2,5-Di(1,1,2,2,2-Pentafluoroethoxy)Aniline is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, is performed to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom purity grades (e.g., >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.