Description

L-Erythro-3-(3,4-Dihydroxyphenyl)Serine is a high-purity, stereochemically defined amino acid derivative of significant interest in advanced pharmaceutical and biochemical research. Its core value lies in its role as a key chiral intermediate and a structural analog of L-DOPA, enabling the synthesis of specialized compounds for neurological and metabolic studies. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require a reliable source of a specific enantiomer for process development and active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, metabolic pathway analysis, and neurotransmitter research due to its structural similarity to catecholamines.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Asymmetric Synthesis: Employed in the development of asymmetric catalytic processes and the preparation of other enantiomerically pure compounds.
• Preclinical Studies: Utilized in in vitro and in vivo studies to investigate pharmacological activity and metabolic fate.

Basic Information

Product Name	L-Erythro-3-(3,4-Dihydroxyphenyl)Serine
CAS No.	34047-62-6
Molecular Formula	C9H11NO6
Molecular Weight	229.19 g/mol
Synonyms	L-DOPS (L-three-DOPS); L-Threo-3,4-Dihydroxyphenylserine; (2S,3R)-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid; Nordox; Droxidopa (precursor); L-Threo-DOPS; Erythro-L-DOPS; 3,4-DiOH-L-Phe-ser
EINECS	Contact for details

Quality Control

Our L-Erythro-3-(3,4-Dihydroxyphenyl)Serine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Erythro isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.