Description

n-Acetyl-L-Citrulline is a chemically modified derivative of the amino acid L-citrulline, designed for enhanced stability and bioavailability. This acetylated form is critical for applications requiring precise metabolic precursors and intermediates in biochemical synthesis. It serves as a key raw material for research and production in the pharmaceutical, nutraceutical, and advanced biochemical sectors, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates targeting nitric oxide pathways and cardiovascular health.
• Dietary Supplement & Nutraceutical Formulations: Incorporated as a stable, bioavailable precursor to L-arginine and nitric oxide in performance and wellness supplements.
• Biochemical Research: Serves as a critical reagent and standard in metabolic studies, enzymatic assays, and cell culture media for investigating urea cycle dynamics.
• Cosmeceutical Ingredients: Utilized in advanced skincare formulations for its potential role in promoting circulation and skin health.
• Veterinary Medicine: Applied in specialized animal health products and nutritional supplements.

Basic Information

Product Name	n-Acetyl-L-Citrulline
CAS No.	33965-42-3
Molecular Formula	C8H15N3O4
Molecular Weight	217.22 g/mol
Synonyms	Nα-Acetyl-L-citrulline; N-Acetylcitrulline; L-Nα-Acetylcitrulline; (2S)-2-Acetamido-5-(carbamoylamino)pentanoic acid; Acetylcitrulline; N-Acetyl-L-citrulline; Ac-Cit-OH
EINECS	Contact for details

Quality Control

Our n-Acetyl-L-Citrulline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the high standards required for pharmaceutical and nutraceutical applications. Certificates of Analysis (COA) are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	+18.0° to +22.0° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.