Description

(6As)-4-Amino-6Aα,7,8,9Aα-Tetrahydro-7α-Hydroxy-6H-Furo[3',2':4,5]Imidazo[1,2-E]Purine-8β-Methanol is a complex, high-purity heterocyclic compound with a fused ring system, serving as a critical advanced pharmaceutical intermediate and research chemical. Its intricate molecular architecture makes it a valuable building block for the synthesis of novel therapeutic agents, particularly in the fields of oncology and antiviral research. This compound is essential for R&D laboratories and pharmaceutical manufacturers engaged in developing next-generation small molecule drugs and exploring new biochemical pathways.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of novel purine and imidazo-purine based active pharmaceutical ingredients (APIs).
• Oncology Research: Used in the discovery and development of targeted cancer therapies due to its role in nucleoside analog synthesis.
• Antiviral Drug Development: Serves as a core scaffold for creating compounds with potential activity against viral enzymes and replication mechanisms.
• Biochemical Research: Employed as a reference standard or probe in enzymatic studies and receptor binding assays to investigate cellular signaling.
• Process Chemistry: Utilized in route scouting and optimization for the scalable synthesis of complex drug candidates.
• Academic Research: A valuable compound for universities and research institutes studying heterocyclic chemistry and medicinal chemistry.

Basic Information

Product Name	(6As)-4-Amino-6Aα,7,8,9Aα-Tetrahydro-7α-Hydroxy-6H-Furo[3',2':4,5]Imidazo[1,2-E]Purine-8β-Methanol
CAS No.	33962-27-5
Molecular Formula	C₁₁H₁₄N₆O₃
Molecular Weight	278.27 g/mol
Synonyms	4-Amino-6aα,7,8,9aα-tetrahydro-7α-hydroxy-6H-furo[3',2':4,5]imidazo[1,2-e]purine-8β-methanol; 8β-(Hydroxymethyl)-4-amino-6aα,7,8,9aα-tetrahydro-7α-hydroxy-6H-furo[3',2':4,5]imidazo[1,2-e]purine; Furo[3',2':4,5]imidazo[1,2-e]purine-8β-methanol derivative; 33962-27-5; A complex fused purine-imidazole-furan derivative.
EINECS	Contact for details

Quality Control

Our (6As)-4-Amino-6Aα,7,8,9Aα-Tetrahydro-7α-Hydroxy-6H-Furo[3',2':4,5]Imidazo[1,2-E]Purine-8β-Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.