Description

Glutathionylspermidine CAS NO 33932-35-3 is a specialized biochemical compound formed by the conjugation of glutathione and spermidine, representing a key intermediate in polyamine metabolism. This molecule is of significant interest in biochemical and pharmaceutical research due to its role in cellular redox regulation and stress response mechanisms. It is primarily utilized by research institutions and pharmaceutical developers focusing on metabolic pathways, antioxidant systems, and novel therapeutic targets.

Application

• Biochemical Research: Used as a critical standard and reagent in studies of polyamine and glutathione metabolic pathways.
• Pharmaceutical Development: Serves as a reference compound and potential intermediate in the discovery of drugs targeting oxidative stress and cellular metabolism.
• Enzymology Studies: Employed as a substrate for enzymes like glutathionylspermidine synthetase and amidase to study reaction kinetics and mechanisms.
• Metabolomics & Biomarker Research: Acts as a target analyte in mass spectrometry-based profiling to understand its role in various physiological and pathological states.
• Antioxidant Mechanism Investigation: Utilized in research exploring the interplay between the glutathione system and polyamines in cellular defense.

Basic Information

Product Name	Glutathionylspermidine
CAS No.	33932-35-3
Molecular Formula	C22H41N8O6S
Molecular Weight	545.68 g/mol
Synonyms	N1-(N-(N-(γ-L-Glutamyl)-L-cysteinyl)glycyl)spermidine; N1-(Glutathionyl)spermidine; Gsp; Glutathionylspermidine disulfide (reduced form); Spermidine glutathione conjugate; L-γ-Glutamyl-L-cysteinylglycyl-spermidine; Trypanothione precursor
EINECS	Contact for details

Quality Control

Our Glutathionylspermidine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay results, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 98% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.