Description

Perhydroantamanide is a fully hydrogenated derivative of the cyclopeptide antamanide, representing a key intermediate and reference standard in advanced pharmaceutical research. Its significance lies in its structural stability and utility for studying peptide conformation, biological activity, and structure-activity relationships. This compound is primarily needed by research institutions and pharmaceutical developers working on peptide-based drug discovery, metabolic studies, and analytical method development.

Application

• Pharmaceutical Research Intermediate: Serves as a critical building block or reference compound in the development of novel peptide therapeutics.
• Biochemical Research: Used as a stable analog to investigate the biological function and binding mechanisms of native antamanide and related peptides.
• Analytical Standard: Employed as a high-purity standard for qualitative and quantitative analysis (e.g., HPLC, LC-MS) in quality control and method validation.
• Structure-Activity Relationship (SAR) Studies: Essential for probing the impact of hydrogenation on peptide conformation, stability, and pharmacological profile.
• Academic & Institutional Research: Utilized in university and government labs for fundamental studies in peptide chemistry and medicinal chemistry.

Basic Information

Product Name	Perhydroantamanide
CAS No.	33906-64-8
Molecular Formula	C64H100N10O10
Molecular Weight	1169.5 g/mol
Synonyms	Hexadecahydroantamanide; Antamanide, perhydro-; Cyclo(-Val1-Pro2-Pro3-Ala4-Phe5-Phe6-Pro7-Pro8-Phe9-Phe10) (all L-, perhydro); Fully hydrogenated antamanide; Perhydro-antamanide; Antamanide Perhydro Derivative
EINECS	Contact for details

Quality Control

Our Perhydroantamanide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant standards for research chemicals, ensuring reliable and traceable material for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.