Description

2-Pyrrolidinecarboxamide,n-Acetyl-,L-(8Ci) is a high-purity chiral intermediate of significant interest in advanced organic synthesis. Its value lies in its role as a key building block for the development of novel pharmaceuticals and bioactive compounds, particularly those targeting the central nervous system. This product is essential for research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for complex synthetic routes. The compound is identified by CAS number 33818-16-5.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of N-acetyl-L-prolinamide and related proline derivatives used in drug discovery.
• Peptidomimetics Research: Serves as a constrained scaffold in the design and synthesis of peptide analogs to improve metabolic stability and bioavailability.
• Neurological Drug Development: Used in the research of potential therapeutic agents for neurological disorders due to its structural similarity to neurotransmitters.
• Asymmetric Catalysis: Employed as a ligand precursor or chiral auxiliary in asymmetric synthesis to induce stereoselectivity.
• Agrochemical Synthesis: A building block for creating novel, biologically active molecules in crop protection research.
• Biochemical Research: Utilized in enzymatic studies and as a standard in analytical method development for related compounds.

Basic Information

Product Name	2-Pyrrolidinecarboxamide,n-Acetyl-,L-(8Ci)
CAS No.	33818-16-5
Molecular Formula	C7H12N2O2
Molecular Weight	156.18 g/mol
Synonyms	N-Acetyl-L-prolinamide; L-N-Acetylprolinamide; (S)-N-Acetylpyrrolidine-2-carboxamide; N-Acetyl-L-proline amide; Ac-L-Pro-NH2; 1-Acetyl-L-proline amide; Nalpha-Acetyl-L-prolinamide; L-Proline, N-acetyl-, amide
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinecarboxamide,n-Acetyl-,L-(8Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), specific rotation, and residual solvents is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.