Description

8-(Trifluoromethyl)-1-Naphthol is a specialized fluorinated naphthol derivative, serving as a high-value intermediate in advanced organic synthesis. Its core value lies in the unique reactivity and electronic properties imparted by the trifluoromethyl group, which is critical for modifying the physical and chemical characteristics of target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and materials science sectors, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, and lipophilicity.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorinated components for electronic displays and organic light-emitting diodes, contributing to improved performance and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal properties, chemical resistance, and surface characteristics.
• Dye & Pigment Intermediate: Utilized in the synthesis of advanced colorants and fluorescent markers with tailored properties.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	8-(Trifluoromethyl)-1-Naphthol
CAS No.	33533-47-0
Molecular Formula	C11H7F3O
Molecular Weight	212.17 g/mol
Synonyms	1-Naphthol, 8-(trifluoromethyl)-; 8-(Trifluoromethyl)naphthalen-1-ol; 1-Hydroxy-8-(trifluoromethyl)naphthalene; 8-Trifluoromethyl-1-naphthol; α-Naphthol, 8-trifluoromethyl-; 8-Trifluoromethyl-α-naphthol
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethyl)-1-Naphthol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.