Description

(2S,3S)-3-Methylglutamic Acid CAS NO 33511-70-5 is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry at the 2 and 3 positions. This compound is a critical chiral building block and intermediate in the synthesis of complex pharmaceuticals, bioactive peptides, and advanced research chemicals. It is primarily utilized by research institutions, pharmaceutical development labs, and fine chemical manufacturers requiring enantiomerically pure materials for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in neurologic and metabolic disorder research.
• Peptide Synthesis: Used as a specialized, non-natural amino acid residue to introduce conformational constraints and enhance the metabolic stability of therapeutic peptides.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies, especially those involving glutamate analogs and metabolic pathways.
• Asymmetric Synthesis Catalyst: Employed as a precursor or ligand in the development of chiral catalysts for stereoselective transformations.
• Reference Standard: High-purity grade material used as an analytical standard for quality control and method development in pharmaceutical analysis.
• Nutraceutical R&D: Investigated for potential applications in specialized nutritional supplements and metabolic modulators.

Basic Information

Product Name	(2S,3S)-3-Methylglutamic Acid
CAS No.	33511-70-5
Molecular Formula	C6H11NO4
Molecular Weight	161.16 g/mol
Synonyms	(2S,3S)-3-Methyl-L-glutamic Acid; (S,S)-3-Methylglutamic Acid; (2S,3S)-3-Methylglutamate; 3-Methyl-L-glutamic Acid; (2S,3S)-3-MGlu; β-Methyl-L-glutamic Acid; (S,S)-β-Methylglutamate
EINECS	Contact for details

Quality Control

Our (2S,3S)-3-Methylglutamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and identity confirmation by IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, assay, and impurity profiles to meet the stringent requirements of pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.