Description

5-Hydroperoxymethyluracil is a specialized organic peroxide derivative of uracil, a fundamental pyrimidine base. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a reactive intermediate and a potential marker for oxidative DNA damage. It is primarily utilized by research institutions and chemical manufacturers engaged in advanced organic synthesis, analytical method development, and the study of nucleic acid chemistry.

Application

• Biochemical Research: Used as a key intermediate or reference standard in studies investigating oxidative stress and DNA damage mechanisms.
• Pharmaceutical Development: Serves as a building block or a model compound in the synthesis of novel nucleoside analogs and potential therapeutic agents.
• Analytical Chemistry: Employed as a high-purity standard for calibrating equipment (e.g., HPLC, LC-MS) used in the detection and quantification of oxidized nucleobases.
• Organic Synthesis: Acts as a reactive peroxide moiety for introducing functional groups into complex molecules in specialized synthetic pathways.
• Cosmeceutical Research: Investigated for its properties in studies related to skin aging and the effects of environmental oxidants.

Basic Information

Product Name	5-Hydroperoxymethyluracil
CAS No.	33499-50-2
Molecular Formula	C5H6N2O4
Molecular Weight	158.11 g/mol
Synonyms	5-(Hydroperoxymethyl)uracil; 5-(Hydroperoxymethyl)-2,4(1H,3H)-pyrimidinedione; 5-HPMU; 5-Hydroperoxymethyl-2,4-dihydroxypyrimidine; Uracil, 5-(hydroperoxymethyl)-
EINECS	Contact for details

Quality Control

Our 5-Hydroperoxymethyluracil is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation and light. Keep away from heat, sparks, open flames, and incompatible materials such as strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.