Description

6-Chloro-L-Tryptophan is a halogenated derivative of the essential amino acid L-tryptophan, distinguished by a chlorine atom at the 6-position of the indole ring. This structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive compounds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications ranging from drug discovery to the synthesis of complex peptides and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents, including serotonin receptor modulators and enzyme inhibitors.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway research to investigate tryptophan metabolism.
• Peptide Synthesis: Incorporated into custom peptides to study structure-activity relationships (SAR) or to create peptides with modified biological properties.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Agrochemical Research: Investigated as an intermediate for developing new plant growth regulators or specialized amino acid-based compounds.
• Nutritional Science Studies: Used in research to understand the effects of halogenated tryptophan analogs on biological systems.

Basic Information

Product Name	6-Chloro-L-Tryptophan
CAS No.	33468-35-8
Molecular Formula	C11H11ClN2O2
Molecular Weight	238.67 g/mol
Synonyms	(S)-2-Amino-3-(6-chloro-1H-indol-3-yl)propanoic acid; L-6-Chlorotryptophan; 6-Chlorotryptophan; 6-Cl-Trp; 6-Chloro-L-Trp; (2S)-2-Amino-3-(6-chloro-1H-indol-3-yl)propanoic acid; 6-Chloroindole-3-alanine
EINECS	Contact for details

Quality Control

Our 6-Chloro-L-Tryptophan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), specific rotation, and residual solvent levels is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity ([α]D)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.