Description

6-Methyl-L-Tryptophan is a non-proteinogenic, methylated derivative of the essential amino acid L-tryptophan. This specialized compound is of significant interest in biochemical research and pharmaceutical development due to its role as a potential metabolic intermediate and enzyme inhibitor. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroscience, metabolic pathway analysis, and the synthesis of novel bioactive molecules. Its unique structure makes it a valuable tool for probing biological systems and developing targeted therapies.

Application

• Biochemical Research: Used as a standard, reference material, or substrate in enzymatic studies and metabolic pathway investigations.
• Pharmaceutical Intermediates: Serves as a key chiral building block in the synthesis of more complex pharmaceutical compounds and potential drug candidates.
• Neuroscience Studies: Investigated for its potential effects on serotonin synthesis and related neurotransmitter pathways due to its structural similarity to tryptophan.
• Microbiology & Fermentation: May be used in microbial culture media as a selective agent or to study amino acid uptake and metabolism in microorganisms.
• Analytical Standards: Employed as a high-purity standard for calibration in analytical methods such as HPLC and LC-MS for accurate quantification in complex matrices.

Basic Information

Product Name	6-Methyl-L-Tryptophan
CAS No.	33468-34-7
Molecular Formula	C₁₂H₁₄N₂O₂
Molecular Weight	218.25 g/mol
Synonyms	(S)-2-Amino-3-(6-methyl-1H-indol-3-yl)propanoic acid; L-6-Methyltryptophan; 6-Methyl-L-Trp; 6-MTrp; (S)-α-Amino-1H-indole-3-propanoic acid, 6-methyl-; 6-Methyl-DL-tryptophan (related); 6-Methylindole-3-alanine
EINECS	Contact for details

Quality Control

Our 6-Methyl-L-Tryptophan is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification by IR spectroscopy, purity assay by HPLC, and specific tests for related substances and residual solvents, to ensure it meets high-purity research-grade standards. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Specific range available on COA
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.