Description

Buspirone Hydrochloride CAS NO 33386-08-2 is a high-purity, fine chemical compound belonging to the azapirone class, primarily recognized for its anxiolytic properties. It serves as a critical active pharmaceutical ingredient (API) and a key reference standard in pharmaceutical research and development. This compound is essential for manufacturers and research institutions focused on central nervous system (CNS) therapeutics, analytical testing, and generic drug formulation.

Application

• Active Pharmaceutical Ingredient (API): Primary use in the formulation of anxiolytic medications.
• Pharmaceutical Reference Standard: Serves as a certified standard for quality control, HPLC, and spectroscopic analysis in laboratories.
• Research & Development: Used in preclinical and clinical studies investigating serotonin (5-HT1A) receptor agonists.
• Generic Drug Manufacturing: A vital component for producing generic versions of branded anxiolytic drugs.
• Analytical Chemistry: Employed as a marker or control substance in method development and validation.
• Biochemical Research: Utilized in studies exploring neurotransmitter systems and neuropharmacology.

Basic Information

Product Name	Buspirone Hydrochloride
CAS No.	33386-08-2
Molecular Formula	C21H31N5O2·HCl
Molecular Weight	421.96 g/mol
Synonyms	Buspirone HCl; MJ-9022-1; 8-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride; Bespar; Buspar; Anxut; Narol; Sporilin; Ansiced
EINECS	Contact for details

Quality Control

Our Buspirone Hydrochloride is manufactured under strict quality management systems, targeting compliance with pharmaceutical-grade standards. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and meet rigorous customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.