Description

4-Chloro-5-(4-Chlorophenyl)-Pyrimidine is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key synthon for the research and production of novel drug candidates, particularly in kinase inhibitor and antiviral agent development.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for functionalized organic materials and ligands for metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	4-Chloro-5-(4-Chlorophenyl)-Pyrimidine
CAS No.	33258-76-3
Molecular Formula	C10H6Cl2N2
Molecular Weight	225.07 g/mol
Synonyms	5-(4-Chlorophenyl)-4-chloropyrimidine; 4-Chloro-5-(p-chlorophenyl)pyrimidine; 4,5-Dichlorophenylpyrimidine; 4-Chloro-5-(4'-chlorophenyl)pyrimidine; Pyrimidine, 4-chloro-5-(4-chlorophenyl)-; 33258-76-3; 4-Chloro-5-(4-chlorophenyl)pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-5-(4-Chlorophenyl)-Pyrimidine is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are supplied with full traceability and are supported by a detailed Certificate of Analysis (COA) for each lot, confirming compliance with customer specifications. We adhere to cGMP principles where applicable, ensuring reliability for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.