Description

3-Nitro-D-Tyrosine is a chemically modified derivative of the amino acid tyrosine, distinguished by the presence of a nitro group at the 3-position of the aromatic ring. This specific modification makes it a valuable chiral building block and a key intermediate in advanced organic synthesis and biochemical research. It is particularly sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel compounds and as a standard in analytical studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic pathways.
• Biochemical Research: Used as a standard or reagent in studies of enzyme activity, protein nitration, oxidative stress pathways, and signal transduction mechanisms.
• Peptide Synthesis: Serves as a modified amino acid building block for the solid-phase or solution-phase synthesis of custom peptides with specific functional properties.
• Proteomics & Analytical Standards: Employed as a reference standard in mass spectrometry, HPLC, and other analytical techniques for the identification and quantification of nitrotyrosine-containing proteins.
• Academic & Industrial R&D: Fundamental research tool in chemistry and life science laboratories for investigating reaction mechanisms and structure-activity relationships.

Basic Information

Product Name	3-Nitro-D-Tyrosine
CAS No.	32988-39-9
Molecular Formula	C9H10N2O5
Molecular Weight	226.19 g/mol
Synonyms	D-3-Nitrotyrosine; (R)-2-Amino-3-(3-nitro-4-hydroxyphenyl)propanoic acid; (R)-3-Nitrotyrosine; D-α-Amino-3-nitro-4-hydroxybenzenepropanoic acid; 3-Nitro-D-tyrosine; D-Tyr(NO2); D-Tyrosine, 3-nitro-; (2R)-2-Amino-3-(3-nitro-4-hydroxyphenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our 3-Nitro-D-Tyrosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.